The role of the organ microenvironment i
โ
Isaiah J. Fidler; Sun-Jin Kim; Robert R. Langley
๐
Article
๐
2007
๐
John Wiley and Sons
๐
English
โ 102 KB
๐ 2 views
## Abstract By the time of diagnosis, primary neoplasms are biologically heterogeneous and contain subpopulations of cells with different metastatic potentials. The pathogenesis of a metastasis consists of many sequential steps that must be completed to produce clinically relevant lesions. During a