The biological properties of E6 and E7 oncoproteins from human papillomaviruses
β Scribed by Raffaella Ghittoni; Rosita Accardi; Uzma Hasan; Tarik Gheit; Bakary Sylla; Massimo Tommasino
- Book ID
- 106558672
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 424 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0920-8569
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## Abstract Over the last two decades, since the initial discovery of human papillomavirus (HPV) type 16 and 18 DNAs in cervical cancers by Dr. Harald zur Hausen (winner of the Nobel Prize in Physiology or Medicine, 2008), the HPVs have been well characterised as causative agents for cervical cance
## Abstract The carcinogenesis of human papillomaviruses type 16 (HPVβ16) is mainly due to its two oncoproteins, E6 and E7. Their carcinogenic features in term of their relationship with Bclβ2 family are still unclear. We thus aimed to analyze the expression of Bclβ2 family members, Bclβ2, Bax, and