DNA vaccines against the human papillomavirus type 16 E6 or E7 oncoproteins
โ Scribed by Wlazlo, Anthony P; Deng, Hongying; Giles-Davis, Wynetta; Ertl, Hildegund C J
- Book ID
- 110019128
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 166 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0929-1903
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Certain human papillomaviruses (HPV), mainly types 16 and 18, have been widely recognized as an essential etiologic factor for the development of carcinoma of the uterine cervix. The early HPV proteins E6 and E7 are consistently expressed in the tumor cells, and cervical-carcinoma patients can devel
## Abstract Human papillomavirus (HPV) infection is associated with cervical cancer. The E2 and E1 papillomavirus proteins are expressed at the early stage of infection and regulate DNA replication. The E2 protein activates and represses transcription from different HPVs promoters. At some stage wh