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The binding of tamoxifen to oestrogen receptor proteins under equilibrium and non-equilibrium conditions

✍ Scribed by R.I. Nicholson; J.S. Syne; C.P. Daniel; K. Griffiths


Book ID
113146213
Publisher
Elsevier Science
Year
1979
Weight
892 KB
Volume
15
Category
Article
ISSN
0014-2964

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The loading of Ku onto a DNA end in a double-strand DNA break is thought to be one of the "rst steps in the non-homologous DNA end joining (NHEJ) pathway, giving it an essential role in the maintenance of genomic integrity. The binding of Ku to DNA is complicated since DNA can accommodate multiple K