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The Binding of Furosemide to Serum Proteins in Elderly Patients: Displacing Effect of Phenprocoumon

✍ Scribed by Andreasen, F. ;Husted, S.

Book ID: 114799715
Publisher: Wiley (Blackwell Publishing)
Year: 2009
Weight: 344 KB
Volume: 47
Category: Article
ISSN: 0001-6683
DOI: 10.1111/j.1600-0773.1980.tb01560.x

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## Abstract Displacement of cephazolin, a highly protein‐bound β‐lactam antibiotic, by sulpha‐phenazole was studied __in vitro__ and __in vivo. In vitro__, the sulphonamide was effective in displacing the antibiotic from its binding sites at the concentration 100–1000 μmol I^−1^. __In vivo__, both