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The binding of anti-DNA antibodies to phosphorothioate oligonucleotides in a solid phase immunoassay

✍ Scribed by David S Pisetsky; Charles F Reich III


Book ID
117326006
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
338 KB
Volume
35
Category
Article
ISSN
0161-5890

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## Abstract A solid phase enzyme immunoassay (EIA) detected anti‐double‐stranded (ds) DNA antibodies in 88% of sera from patients classified clinically as having active systemic lupus erythematosus (SLE) without renal symptoms and 93% with renal disease. Fifty‐six percent of sera from patients with