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The beta-isoform of neuronal nitric oxide synthase (nNOS) lacking the PDZ domain is localized at the sarcolemma

✍ Scribed by Oliver Baum; Simon Schläppi; Felicitas A. Huber-Abel; Alexander Weichert; Hans Hoppeler; Andreas Zakrzewicz


Book ID
113622745
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
705 KB
Volume
585
Category
Article
ISSN
0014-5793

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## Abstract α1‐syntrophin is a PDZ‐containing dystrophin‐associated protein, expressed predominantly in striated muscle and brain. α1‐syntrophin null mice generated by gene targeting technique showed no overt muscular dystrophic phenotype. Though other dystrophin‐associated proteins were localized