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The Bcl-2 Protein Family

โœ Scribed by Bruno Antonsson; Jean-Claude Martinou


Book ID
115603639
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
141 KB
Volume
256
Category
Article
ISSN
0014-4827

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REVIEW Bcl-2 and related cytoplasmic proteins are key regulators of apoptosis, the cell suicide program critical for development, tissue homeostasis, and protection against pathogens. Those most similar to Bcl-2 promote cell survival by inhibiting adapters needed for activation of the proteases (ca