The Bcl-2 Protein Family: Arbiters of Ce
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Adams, J. M.
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Article
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1998
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American Association for the Advancement of Scienc
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English
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REVIEW Bcl-2 and related cytoplasmic proteins are key regulators of apoptosis, the cell suicide program critical for development, tissue homeostasis, and protection against pathogens. Those most similar to Bcl-2 promote cell survival by inhibiting adapters needed for activation of the proteases (ca