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The basic helix–loop–helix transcription factor TAL1/SCL inhibits the expression of the p16INK4A and pTα genes

✍ Scribed by Anders Hansson; Christina Manetopoulos; Jan-Ingvar Jönsson; Håkan Axelson

Book ID
116287534
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
315 KB
Volume
312
Category
Article
ISSN
0006-291X

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## Abstract Parathyroid hormone (PTH) is an essential regulator of endochondral bone formation and an important anabolic agent for the reversal of bone loss. PTH mediates its functions in part by regulating binding of the bone‐related activating transcription factor 4 (ATF4) to the osteoblast‐speci