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Functional and Structural Characterization of the Human Gene BHLHB5, Encoding a Basic Helix-Loop-Helix Transcription Factor

✍ Scribed by Zheng-Ping Xu; Amalia Dutra; Christine M. Stellrecht; Chengyan Wu; Joram Piatigorsky; Grady F. Saunders

Book ID
115615683
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
421 KB
Volume
80
Category
Article
ISSN
0888-7543

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Basic helix-loop-helix (bHLH) transcription factors have been shown to play an important role in controlling cell type determination and differentiation. TWIST, a member of the bHLH transcription factor family, is involved in the development of mesodermally derived tissue, including the skeleton. We