The Basic-Helix-Loop-Helix Transcription Factor HAND2 Directly Regulates Transcription of the Atrial Naturetic Peptide Gene
β Scribed by Bijoy D. Thattaliyath; Beth A. Firulli; Anthony B. Firulli
- Book ID
- 115633479
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 921 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0022-2828
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## Abstract Mammalian autonomic nervous system (ANS) development requires the combinatorial action of a number of transcription factors, which include Mash1, Phox2b, and GATA3. Here we show that the bHLH transcription factor, __Hand2__ (dHAND), is expressed concurrently with __Mash1__ during sympat
Basic helix-loop-helix (bHLH) transcription factors have been shown to play an important role in controlling cell type determination and differentiation. TWIST, a member of the bHLH transcription factor family, is involved in the development of mesodermally derived tissue, including the skeleton. We