Environmentally friendly oxidizing agents such as hydrogen peroxide or dioxygen can be used today in catalytic versions of the almost one century old Baeyer-Villiger oxidation with transition metal complexes as catalysts. On the right is a sketch of a possible mechanism for this reaction with a plat
The Baeyer–Villiger oxidation of ketones: A paradigm for the role of soft Lewis acidity in homogeneous catalysis
✍ Scribed by Rino A. Michelin; Paolo Sgarbossa; Alessandro Scarso; Giorgio Strukul
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 707 KB
- Volume
- 254
- Category
- Article
- ISSN
- 0010-8545
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Multi-metallic hydrotalcites consisting of magnesium, aluminum, and iron, or copper elements were prepared, which catalyzed the Baeyer-Villiger oxidation using a combination system of molecular oxygen and benzaldehyde. In particular, the Mg-Al\(\mathrm{Fe}-\mathrm{CO}_{3}\) hydrotalcite efficiently
Oxidation of 2 with m-chloroperbenzoic acid in the presence of SnCI4 at -78 °C followed by hydrolysis afforded optically active 4 in a quantitative yield. The enantiomeric excess (ee) of 4 largely depended on the reaction solvent, the chiral diol part, the Lewis acid and its amount. The best ee was