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The Aza-[2,3]-Wittig Sigmatropic Rearrangement of Acyclic Amines: Scope and Limitations of Silicon Assistance

✍ Scribed by Anderson, James C.; Flaherty, Alice; Swarbrick, Martin E.


Book ID
127201373
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
70 KB
Volume
65
Category
Article
ISSN
0022-3263

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The aza-[2,3]-Wittig sigmatropic rearran
✍ James C Anderson; Philippe Dupau; D Craig Siddons; Stephen C Smith; Martin E Swa πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 134 KB

The aza-[2,3]-Wittig sigmatropic rearrangement of Z(C)-alkenes can be achieved through the use of a trimethylsilyl anion stabilising group. The major diastereoisomer complements previous results and allows access to each diastereoisomer of the homoallylic amine products. A transition state model is