The autoreactivity of B cells in hereditary angioedema due to C1 inhibitor deficiency
β Scribed by A. Kessel; R. Peri; R. Perricone; M. D. Guarino; Z. Vadasz; R. Novak; T. Haj; S. Kivity; E. Toubi
- Book ID
- 108701531
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 292 KB
- Volume
- 167
- Category
- Article
- ISSN
- 0009-9104
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Hereditary angioedema (HAE) is due to a variety of defects in the C1 inhibitor gene (C1NH gene), including approximately 20% of partial deletions/duplications whose boundaries are usually within Alu repeats. To ensure complete molecular characterization of C1 inhibitor deficiencies a fluorescent mul
Communicated by Mark H. Paalman Hereditary angioedema (HAE) is a disorder characterised by recurrent attacks of localized subcutaneous or submucosal edema. It is inherited in an autosomal dominant fashion and caused by a deficiency of C1 inhibitor (C1 inh, or C1NH). Most patients with HAE have an ab