Alterations of coagulation and fibrinolysis in patients with angioedema due to C1-inhibitor deficiency
โ Scribed by M. van Geffen; M. Cugno; P. Lap; A. Loof; M. Cicardi; W. van Heerde
- Book ID
- 108701544
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 362 KB
- Volume
- 167
- Category
- Article
- ISSN
- 0009-9104
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๐ SIMILAR VOLUMES
Hereditary angioedema (HAE) is caused by mutations in the C1 inhibitor gene (SERPING1, C1NH) and the result is C1 inhibitor deficiency, either in levels or function. We have searched exon 8 for mutations by direct sequencing and analyzed the rest of the exons by SSCP in 87 Spanish families affected
Communicated by Mark H. Paalman Hereditary angioedema (HAE) is a disorder characterised by recurrent attacks of localized subcutaneous or submucosal edema. It is inherited in an autosomal dominant fashion and caused by a deficiency of C1 inhibitor (C1 inh, or C1NH). Most patients with HAE have an ab