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The AU-Rich 3′ Untranslated Region of Human MDR1 mRNA Is an Inefficient mRNA Destabilizer

✍ Scribed by Rebecca D. Prokipcak; Afshin Raouf; Chunja Lee


Book ID
115584202
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
233 KB
Volume
261
Category
Article
ISSN
0006-291X

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Syndecan-1 is a transmembrane proteoglycan expressed predominantly in epithelial cells. Studies with immunohistochemistry have shown that syndecan-1 expression is reduced in carcinoma derived from human epidermis. Here we show that syndecan-1 mRNA, which is abundant in human primary keratinocyte (HK