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The Asymmetric Synthesis of (3 S ,4 R ,5 S )-3-Amino-4,5- O -isopropylidenedioxycyclopentene

✍ Scribed by Trost, Barry M.; Sorum, Mark T.


Book ID
121326187
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
151 KB
Volume
7
Category
Article
ISSN
1083-6160

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Stereoselective synthesis of (2S,3S,4R,5
✍ Makoto Oba; Tsutomu Terauchi; Jun Hashimoto; Tomohiro Tanaka; Kozaburo Nishiyama πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 French βš– 227 KB

A catalytic deuteration of protected 3,4-dehydro-L-proline using RuCI2(PPh3) 3 followed by RuO~-oxidation gave a 3,4-dideuterated L-pyroglutamic acid derivative which is considered to be a promising precursor for various deuterated amino acids. The present study demonstrates a stereoselective reduct