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The association of α-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study

✍ Scribed by Laura J. Rasmussen-Torvik; Mary Cushman; Michael Y. Tsai; Yan Zhang; Susan R. Heckbert; Wayne D. Rosamond; Aaron R. Folsom

Book ID
116913622
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
133 KB
Volume
121
Category
Article
ISSN
0049-3848

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The association of α-fibrinogen Thr312Al
The association of α-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study
✍ Laura J. Rasmussen-Torvik; Mary Cushman; Michael Y. Tsai; Yan Zhang; Susan R. He 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 133 KB

## Introduction: The alpha-fibrinogen thr312ala variant has been shown to influence clot structure through increased factor xiii cross-linking and formation of thicker fibrin fibers. however, the effect of this common variant on risk of venous thromboembolism (vte) is unclear. this paper reports th