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The association of polymorphisms in DNA base excision repair genesXRCC1,OGG1andMUTYHwith the risk of childhood acute lymphoblastic leukemia

✍ Scribed by M. Stanczyk; T. Sliwinski; M. Cuchra; M. Zubowska; A. Bielecka-Kowalska; M. Kowalski; J. Szemraj; W. Mlynarski; I. Majsterek

Publisher
Springer
Year
2010
Tongue
English
Weight
229 KB
Volume
38
Category
Article
ISSN
0301-4851

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## Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The genetic factors underlying the susceptibility to this disease remain elusive. The enzymes CYP2E1, MPO and NQO1 are involved in the biotransformation of a variety of xenobiotics present in organic solvents, tobac