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Genetic polymorphisms in the DNA repair genesXRCC1,XRCC2andXRCC3and risk of breast cancer in Cyprus

✍ Scribed by Maria A. Loizidou; Thalia Michael; Susan L. Neuhausen; Robert F. Newbold; Yiola Marcou; Eleni Kakouri; Maria Daniel; Panayiotis Papadopoulos; Simos Malas; Kyriacos Kyriacou; Andreas Hadjisavvas


Publisher
Springer US
Year
2008
Tongue
English
Weight
167 KB
Volume
112
Category
Article
ISSN
0167-6806

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Polymorphisms inRAD51, XRCC2andXRCC3gene
✍ Renata Krupa; Tomasz Sliwinski; Maria Wisniewska-Jarosinska; Jan Chojnacki; Maja πŸ“‚ Article πŸ“… 2010 πŸ› Springer 🌐 English βš– 241 KB

XRCC2 and XRCC3 proteins are structurally and functionally related to RAD51 which play an important role in the homologous recombination, the process frequently involved in cancer transformation. In our previous work we show that the 135G>C polymorphism (rs1801320) of the __RAD51__ gene can modify t