The myelin basic proteins are a set of peripheral membrane polypeptides which play an essential role in myelination. Their most well-documented property is the unique ability to 'seal' the cytoplasmic aspects of the myelin membrane, but this is probably not the only function for these highly charged
The association of myelin basic protein with itself and other proteins
β Scribed by John E. Moskaitis; Lisa C. Shriver; Anthony T. Campagnoni
- Book ID
- 105021289
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 846 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0364-3190
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The interaction of myelin basic protein (MBP) and proteolipid protein (PLP) was studied using a microtitre well binding assay and the ligand-blot overlay technique. The binding of iodinated PLP to MBP that was immobilized on microtitre wells was saturable and reversible. Its selectivity was investig
The structural characteristics of myelin basic protein (MBP) involved in protein-protein and protein-lipid interactions were investigated. Rabbit MBP could bind calmodulin (CaM) in the presence of Ca2+ to form a complex that remained undissociated in 8 M urea. However, no tight complex formation was