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The Association of CCND1 Overexpression and Cisplatin Resistance in Testicular Germ Cell Tumors and Other Cancers

✍ Scribed by Elodie E. Noel; Marc Yeste-Velasco; Xueying Mao; Jackie Perry; Sakunthala C. Kudahetti; Ningfeng F. Li; Swee Sharp; Tracy Chaplin; Liyan Xue; Alan McIntyre; Ling Shan; Thomas Powles; R. Tim D. Oliver; Bryan D. Young; Janet Shipley; Daniel M. Berney; Simon P. Joel; Yong-Jie Lu

Book ID
117971094
Publisher
American Society for Investigative Pathology
Year
2010
Tongue
English
Weight
585 KB
Volume
176
Category
Article
ISSN
0002-9440

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## Abstract Testicular germ‐cell tumors (TGCTs) show exquisite sensitivity to cisplatin‐based chemotherapy, and therefore this is considered a good model system for studying the mechanism of chemotherapy resistance. Although the genetic alterations related to TGCT have been well studied, little is