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The assessment of bioequivalence in a two-period cross-over design: Development of a simple BASIC program

โœ Scribed by I. Meineke; C. de Mey


Book ID
113291268
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
138 KB
Volume
35
Category
Article
ISSN
0169-2607

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A practical approach for the assessment
โœ Jouni Vuorinen ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB ๐Ÿ‘ 2 views

The two-period cross-over design with two sequences of drug administration is a standard experimental design when bioequivalence of one test formulation is to be assessed in comparison with a reference formulation. Previously, an approach based on Fieller's confidence interval has been presented for