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The Art of Drug Synthesis || Second-Generation HMG-CoA Reductase Inhibitors

✍ Scribed by Johnson, Douglas S.; Li, Jie Jack


Book ID
120275507
Publisher
John Wiley & Sons, Inc.
Year
2007
Tongue
English
Weight
794 KB
Edition
1
Category
Article
ISBN
0471752150

No coin nor oath required. For personal study only.

✦ Synopsis


The Role Of Medicinal Chemistry In Drug Discovery / John A. Lowe Iii -- Process Research: How Much? How Soon? / Neal G. Anderson -- Aromatase Inhibitors For Breast Cancer : Exemestane (aromasin), Anastrozole (arimidex), And Letrozole (femara) / Jie Jack Li -- Quinolone Antibiotics : Levofloxacin (levaquin), Moxifloxacin (avelox), Gemifloxacin (factive), And Garenoxacin (t-3811) / Chris Limberakis -- Triazole Antifungals : Itraconazole (sporanox), Fluconazole (diflucan), Voriconazole (vfend), And Fosfluconazole (prodif) / Andrew S. Bell -- Non-nucleoside Hiv Reverse Transcriptase Inhibitors / Arthur Harms -- Neuraminidase Inhibitors For Influenza : Oseltamivir Phosphate (tamiflu) And Zanamivir (relenza) / Douglas S. Johnson And Jie Jack Li -- Peroxisome Proliferator-activated Receptor (ppar) Agonists For Type 2 Diabetes / Jin Li -- Angiotensin At1 Antagonists For Hypertension / Larry Yet -- Leading Ace Inhibitors For Hypertension / Victor J. Cee And Edward J. Olhava -- Dihydropyridine Calcium Channel Blockers For Hypertension / Daniel P. Christen -- Second-generation Hmg-coa Reductase Inhibitors / Jeffrey A. Pfefferkorn -- Cholesterol Absorption Inhibitors: Ezetimibe (zetia) / Stuart B. Rosenblum -- Dual Selective Serotonin And Norepinephrine Reuptake Inhibitors (ssnris) For Depression / Marta PiΓ±eiro-nΓΊΓ±ez -- Gaba Receptor Agonists For Insomnia : Zolpidem (ambien), Zaleplon (sonata), Eszopiclone (estorra, Lunesta), And Indiplon / Peter R. Guzzo -- Ligands: Neurontin (gabapentin) And Lyrica (pregabalin) / Po-wai Yuen -- Approved Treatments For Attention Deficit Hyperactivity Disorder : Amphetamine (adderall), Methylphenidate (ritalin), And Atomoxetine (straterra) / David L. Gray. Edited By Douglas S. Johnson, Jie Jack Li. Includes Bibliographical References And Index.


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Synthesis of a novel HMG-COA reductase i
✍ E. Baader; W. Bartmann; G. Beck; A. Bergmann; H. Jendralla; K. Kesseler; G. Wess πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 120 KB

The synthesis of a new 3-hydroxy-3-methylglutaryl coenzyme A reduc-----tase inhibitor starting from 4,4' -difluorobenzophenone is described. Mevinolin 1 and its congeners are potent inhibitors of 3-hydroxy-3-methyl-