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The application of tissue adhesives in small bowel anastomoses

✍ Scribed by Nicholas J. Petrelli; Howard Cohen; Dwicht Derisi; Julian L. Ambrus; Phyllis Williams

Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
226 KB
Volume
19
Category
Article
ISSN
0022-4790

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✦ Synopsis

Abstract

One layer everted end‐to‐end anastomosis was performed on the small bowel of mongrel dogs. Cultures of Serratia marcescens were injected into the lumen. Twenty‐four hours later the animals were reexplored, and peritoneal cultures were observed. In animals where Fibrin Seal (consisting of fibrinogen, cold insoluble globulin, factor XIII, platelet growth factor, antiplasmin, thrombin, and calcium chloride) was applied to the suture line, negative cultures were found except for two experiments in which dehiscence or contamination from the Serratia injection site occurred.

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