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The application of hepatocyte culture to the identification of pathways of drug metabolism: Studies with pindolol and fluperlapine

โœ Scribed by Alan J. Paine; G. Maurer; B.R. von Wartburg

Book ID
115777842
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
221 KB
Volume
33
Category
Article
ISSN
0006-2952

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## Abstract The regulation of drug metabolic activity of cultured hepatocytes can be applied to the evaluation of pharmacokinetics, analysis of drug delivery and the bioartificial liver system. It is very difficult to maintain the drug metabolic activity mediated by cytochrome Pโ€450 (CYP) 3A. Recen