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Development of radioimmunoassays for trifluoperazine and their application to metabolic studies of the drug

โœ Scribed by K.K. Midha; E.M. Hawes; G. Rauw; G. Mckay; J.K. Cooper; H.U. Shetty

Book ID
119086033
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
662 KB
Volume
9
Category
Article
ISSN
0160-5402

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Radioimmunoassay for the sulfoxide metabolite of trifluoperazine and its application to a kinetic study in humans
โœ M. Aravagiri; E. M. Hawes; K. K. Midha ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 653 KB

Antibodies were produced in rabbits immunized with 10- [[3-[4-(2-carboxyethyl)-I-piperazinyl] -propyl]] -2-trifluoromethyl-IOH-phenothiazine sulfoxide-bovine serum albumin conjugate. The subsequently developed radioimmunoassay (RIA) procedure enables, for the first time, the quantitation of the sulf