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The application of Fourier-transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials

✍ Scribed by A.M. Tudor; C.D. Melia; J.S. Binns; P.J. Hendra; S. Church; M.C. Davies

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
236 KB
Volume
8
Category
Article
ISSN
0731-7085

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✦ Synopsis

Near infrared Fourier-transform (FT) Raman spectroscopy is shown to be a useful spectroscopic tool for the molecular structural analysis of drugs and biomedical polymers. The technique has been applied to the non-invasive investigation of the hydrolytic degradation of a biodegradable polymer in water over a period of 15 days and to the analysis of a drug within a polymer vehicle over a wide drug concentration range. This work demonstrates the potential value of FT Raman spectroscopy in the field of pharmaceutical science.

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