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The APOE-491 A/T promoter polymorphism effect on cognitive profile of Alzheimer's patients

โœ Scribed by A. Valenza; A. Bizzarro; C. Marra; A. Lauria; V. Guglielmi; C. Rossi; F.D. Tiziano; C. Brahe; C. Masullo


Book ID
116772079
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
146 KB
Volume
472
Category
Article
ISSN
0304-3940

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Effect of the APOE-491A/T promoter polym
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## Abstract The apolipoprotein E (APOE) gene is involved in lipid transport. A common polymorphism in this gene with the APOE\*2, APOE\*3, and APOE\*4 alleles influences plasma levels of apolipoprotein E and cholesterol. Besides its role in lipid transport, the APOE\*4 allele is a genetic risk fact