Germline mutations in the tumor-suppresor APC gene are associated with hereditary familial adenomatous polyposis (FAP) and somatic mutations are common in sporadic colorectal cancer. In this study, we report the identification of three novel germline mutations: 1682-1683insA, 3252-3253insAT, 3544A>T
The APC (adenomatous polyposis coli) gene: A novel mutation in an FAP patient and a DdeI polymorphism in the 5′ noncoding region
✍ Scribed by Takahiro Mori; Hiroki Nagase; Takahisa Aoki; Hirofumi Arakawa; Tetsuro Nishihira; Shozo Mori; Yusuke Nakamura
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 351 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1059-7794
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