𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The antitumor activity of the platinum complex D-17872 is associated with tumor cell differentiation

✍ Scribed by Hans Rainer Maurer; Christine Echarti; Rainer Voegeli; Jörg Pohl; Peter Hilgard

Publisher
Springer
Year
1993
Tongue
English
Weight
973 KB
Volume
32
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Immortalization of human WI38 cells is a
Immortalization of human WI38 cells is associated with differential activation of the c-myc origins
✍ Liang Tao; Zhifeng Dong; Maria Zannis-Hadjopoulos; Gerald B. Price 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 251 KB

## Abstract To study the possible relationships between origin activities and cellular processes leading to malignancy, we used an isogenic system of human embryo lung fibroblast cells WI38 and a SV40‐transformed variant, WI38 VA13 2RA (WI38(SV40)). We found that the activities of all initiation si

Differentiation of EL4 lymphoma cells by
Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG-M and the tumor-associated antigen HTgp-175
✍ Pieter Rottiers; Tine Verfaillie; Roland Contreras; Hilde Revets; Marjory Desmed 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 135 KB

## Progression to malignancy of transformed cells involves complex genetic alterations and aberrant gene expression patterns. While aberrant gene expression is often caused by alterations in individual genes , the contribution of the tumoral environment to the triggering of this gene expression is

Resistance to 1,25D-induced differentiat
Resistance to 1,25D-induced differentiation in human acute myeloid leukemia HL60-40AF cells is associated with reduced transcriptional activity and nuclear localization of the vitamin D receptor
✍ Edward Garay; Robert Donnelly; Xuening Wang; George P. Studzinski 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 438 KB

## Abstract The anti‐neoplastic effects of 1,25‐dihydroxyvitamin D~3~ (1,25D) are well documented in numerous tumor cell systems and animal models of cancer. However, despite this pre‐clinical success, the clinical use of 1,25D is currently impeded by the dose‐limiting hypercalcemia, and the risk o

The differential expression of H-2K vers
The differential expression of H-2K versus H-2D antigens, distinguishing high- metastatic from low- metastatic clones, is correlated with the immunogenic properties of the tumor cells
✍ Lea Eisenbach; Nurit Hollander; Lea Greenfeld; Hadas Yakor; Shraga Segal; Michae 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 French ⚖ 700 KB

Two clones of the 3LL Lewis lung carcinoma, a lowmetastatic clone A9 and a high-metastatic clone DIZZ, were studied for MHC expression and immunogenic p r o p erties. Using monoclonal antibodies, we demonstrated that the A9 clone expresses both the H-2Kb and the H-2Db. whereas the D I22 expresses o