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The antithrombotic effect of a novel hirudin derivative after reconstruction of carotid artery in rabbits

✍ Scribed by Wei Feng Lu; Wei Mo; Zhenjie Liu; Wei Guo Fu; Da Qiao Guo; Yu Qi Wang; Hou Yan Song


Book ID
116914412
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
436 KB
Volume
126
Category
Article
ISSN
0049-3848

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We examined the antithrombotic effect of KBT-3022, a novel antiplatelet agent, on photochemically induced arterial thrombosis in the guinea-pig saphenous artery, and compared its effect with that of aspirin and that of ticlopidine. Pretreatment with KBT-3022 [0.1 mg (0.2 Β΅mole), 0.3 mg (0.7 Β΅mole),