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The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro

✍ Scribed by Kontek, Renata; Jakubczak, Marta; Matlawska-Wasowska, Ksenia

Book ID: 121393149
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 722 KB
Volume: 28
Category: Article
ISSN: 0887-2333
DOI: 10.1016/j.tiv.2013.11.007

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## Abstract The antioxidant and pro‐oxidant properties of ascorbic acid (vitamin C) and the water‐soluble analogue of __α__‐tocopherol (trolox) were compared. Trolox has advantages over __α__‐tocopherol, the latter being only lipid‐soluble due to the presence of a carboxyl group __in lieu__ of a ph