The antinociceptive effect of 4-substituted derivatives of 5-(4-chlorophenyl)-2-(morpholin-4-ylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione in mice
✍ Scribed by Joanna, Listos; Talarek, Sylwia; Orzelska, Jolanta; Fidecka, Sylwia; Wujec, Monika; Plech, Tomasz
- Book ID
- 121590801
- Publisher
- Springer-Verlag
- Year
- 2013
- Tongue
- English
- Weight
- 237 KB
- Volume
- 387
- Category
- Article
- ISSN
- 0028-1298
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📜 SIMILAR VOLUMES
In the title compound, C 15 H 19 N 5 OS, the morpholine ring adopts a chair conformation. The mean plane of the pyridine ring makes a dihedral angle of 35.16 (7) with the triazole ring plane.
## Abstract magnified image Various 4‐amino‐2,3‐dihydro‐4__H__‐triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short time and at reduced