The crude methanol extracts of three species of the genus Hypericum (H. brasiliense, H. caprifoliatum and H. myrianthum) native to South Brazil were evaluated for the antidepressant activity according to the forced swimming test, a classical animal model for antidepressant drug screening. Among the
The antiinflammatory effect of some species from South America
✍ Scribed by Liliana Muschietti; Virginia Martino; Graciela Ferraro; Jorge Coussio; Laura Segura; Carmen Cartañá; Salvador Cañigueral; Tomás Adzet
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 253 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
Extracts (aqueous, methanol and dichloromethane) from Ambrosia tenuifolia, Aristolochia triangularis, Bacclraris tucumanensis, Campyloneuron phyllitidis and Eupatorium christieanum were screened for antiinflammatory activity. On the croton oil induced mouse ear oedema test, the highest activities were exhibited by dichloromethane extracts assayed, especially those of Baccharis tucumanensis and Campyloneuron phyllitidi. On the carrageenan mouse paw oedema test, Baccharis tucumanensis and Campyloneuron phyllitidis showed the highest activity.
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The present work showed a significant antinociceptive activity in the tannin fraction (TF) extracted from the bark of Myracrodruon urundeuva Fr. All. This inhibitory effect was demonstrated not only against abdominal contractions but also in the formalin test in mice. In the first case, at doses of