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The anticonvulsant activity of d-cycloserine is specific for tonic convulsions

✍ Scribed by Steven L. Peterson; Nathan D. Schwade


Book ID
103932356
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
758 KB
Volume
15
Category
Article
ISSN
0920-1211

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This study evaluated the anticonvulsant activity of D-cycloserine against maximal electroshock seizures in rats. Systematically administered D-cycloserine (i.p.) inhibited maximal electroshock-induced tonic hindlimb extension in a dose-dependent manner with an ED50 of 153 mg/kg. No neurological defi