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Differential effects of glycine on the anticonvulsant activity of D-cycloserine and L-701,324 in mice

✍ Scribed by Piotr, Wlaź; Ewa, Poleszak

Book ID
122206752
Publisher
Elsevier
Year
2011
Tongue
English
Weight
137 KB
Volume
63
Category
Article
ISSN
1734-1140

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✍ Steven L. Peterson 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 877 KB

This study evaluated the anticonvulsant activity of D-cycloserine against maximal electroshock seizures in rats. Systematically administered D-cycloserine (i.p.) inhibited maximal electroshock-induced tonic hindlimb extension in a dose-dependent manner with an ED50 of 153 mg/kg. No neurological defi