Signaling by the Mpl receptor involves I
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Ying Zhang; Shishinn Sun; Zhengyu Wang; Alexander Thompson; Yulia Kaluzhny; Jeff
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Article
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2002
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John Wiley and Sons
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English
⚖ 287 KB
## Abstract Binding of tumor necrosis factor‐α (TNF‐α) to its receptor activates IKK complex, which leads to inducement of NF‐κB activity. Here we report that activation of Mpl ligand is also linked to IKK and NF‐κB activity. Mpl ligand, also known as thrombopoietin (TPO) or megakaryocyte growth an