Phosphatidylinositol 3-kinase signaling
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Jolyon Terragni; Julie R Graham; Kenneth W Adams; Michael E Schaffer; John W Tul
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Article
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2008
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BioMed Central
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English
⚖ 541 KB
## Background Phosphatidylinositol (PI) 3-kinase is activated by a variety of growth factor receptors and the PI 3-kinase/Akt signaling pathway is a key regulator of cell proliferation and survival. The downstream targets of PI 3-kinase/Akt signaling include direct regulators of cell cycle progress