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The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines

✍ Scribed by Quan Liao; Fumiaki Ozawa; Helmut Friess; Arthur Zimmermann; Shinichi Takayama; John C. Reed; Jörg Kleeff; Markus W. Büchler


Book ID
117103267
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
864 KB
Volume
503
Category
Article
ISSN
0014-5793

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## Abstract Pancreatic adeniocarcinoma is among the deadliest of human cancers. Apigenin, an antitumor flavonoid, inhibits pancreatic cancer cell proliferation in vitro. Geminin is a recently identified novel protein that plays a critical role in preventing abnormal DNA replication by binding to an