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Biglycan Is Overexpressed in Pancreatic Cancer and Induces G1-Arrest in Pancreatic Cancer Cell Lines

โœ Scribed by Christoph K. Weber; Gerrit Sommer; Patrick Michl; Heiko Fensterer; Martina Weimer; Frank Gansauge; Gerhard Leder; Guido Adler; Thomas M. Gress


Book ID
119756343
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
883 KB
Volume
121
Category
Article
ISSN
0016-5085

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## Abstract Pancreatic adeniocarcinoma is among the deadliest of human cancers. Apigenin, an antitumor flavonoid, inhibits pancreatic cancer cell proliferation in vitro. Geminin is a recently identified novel protein that plays a critical role in preventing abnormal DNA replication by binding to an