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The analysis of the clastogenic effect of environmental chemicals in human lymphocytes by means of premature chromosome condensation

โœ Scribed by J. Dresp; M. Bauchinger


Book ID
113251380
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
88 KB
Volume
182
Category
Article
ISSN
0165-1161

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The Clastogenic effect of Pyrimethamine
โœ รœ. Egeli; G. Erdogan ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 973 KB

In this study the clastogenic effect of pyrimethamine (Daraprim), a folic acid antagonist used for the treatment of toxoplasmosis and malaria on human chromosomes, was investigated. Pyrimethamine was added to in vitro lymphocyte cultures at six different concentrations: 0.05 (normal therapeutic dose