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The Anabolic Effects of Parathyroid Hormone

✍ Scribed by M. R. Rubin; F. Cosman; F. Cosman; R. Lindsay; R. Lindsay; J. P. Bilezikian; J. P. Bilezikian

Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
167 KB
Volume
13
Category
Article
ISSN
0937-941X

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## Abstract Secreted frizzled‐related protein (sFRP)‐1 is a Wnt antagonist that when deleted in mice leads to increased trabecular bone formation in adult animals after 13 weeks of age. Treatment of mice with parathyroid hormone (PTH) also increases trabecular bone formation, and some of the anabol