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The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications

✍ Scribed by Claudio Russo; Valentina Venezia; Emanuela Repetto; Mario Nizzari; Elisabetta Violani; Pia Carlo; Gennaro Schettini


Book ID
116327597
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
250 KB
Volume
48
Category
Article
ISSN
0165-0173

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Amyloid precursor protein intracellular domain (AICD) is one of the potential candidates in deciphering the complexity of Alzheimer’s disease. It plays important roles in determining cell fate and neurodegeneration through its interactions with several adaptors. The presence or absence of phosphoryl