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The ALDH2 and 5-HT2A genes interacted in bipolar-I but not bipolar-II disorder

✍ Scribed by Sheng-Yu Lee; Shiou-Lan Chen; Yun-Hsuan Chang; Chun-Hsieh Chu; San-Yuan Huang; Nian-Sheng Tzeng; Chen-Lin Wang; Shih-Hsien Lin; I Hui Lee; Tzung Lieh Yeh; Yen Kuang Yang; Ru-Band Lu

Book ID: 116842368
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 223 KB
Volume: 38
Category: Article
ISSN: 0278-5846
DOI: 10.1016/j.pnpbp.2012.04.005

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We selected 42 patients with bipolar disorder type I (BPI) and 40 healthy controls for genetic analysis of DNA polymorphisms in the serotonin receptor 2c (5-HTR2c) and serotonin transporter (5-HTT) genes. No significant associations were found in the total patient sample. However, when the individua