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The Akt of CD28 costimulation of T cells

✍ Scribed by Yoji Shimizu


Book ID
117786871
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
16 KB
Volume
22
Category
Article
ISSN
1471-4906

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πŸ“œ SIMILAR VOLUMES


CD28/B7 SYSTEM OF T CELL COSTIMULATION
✍ Lenschow, Deborah J.; Walunas, Theresa L.; Bluestone, Jeffrey A. πŸ“‚ Article πŸ“… 1996 πŸ› Annual Reviews 🌐 English βš– 193 KB
CD28/B7 SYSTEM OF T CELL COSTIMULATION
✍ Lenschow, Deborah J.; Walunas, Theresa L.; Bluestone, Jeffrey A. πŸ“‚ Article πŸ“… 1996 πŸ› Annual Reviews 🌐 English βš– 193 KB

β–ͺ Abstract  T cells play a central role in the initiation and regulation of the immune response to antigen. Both the engagement of the TCR with MHC/Ag and a second signal are needed for the complete activation of the T cell. The CD28/B7 receptor/ligand system is one of the dominant costimulatory pat

Costimulation of human CD28– T cells by
✍ Jacob Bukczynski; Tao Wen; Tania H. Watts πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 305 KB

## Abstract The T cell surface protein CD28 provides a critical costimulatory signal for T cell activation. With age, humans accumulate increasing numbers of CD28^–^ T cells, and this loss of CD28 expression is exacerbated certain disease states, such as HIV infection, autoimmune conditions or canc