CD28/B7 SYSTEM OF T CELL COSTIMULATION
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Lenschow, Deborah J.; Walunas, Theresa L.; Bluestone, Jeffrey A.
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Article
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1996
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Annual Reviews
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English
β 193 KB
βͺ Abstractβ T cells play a central role in the initiation and regulation of the immune response to antigen. Both the engagement of the TCR with MHC/Ag and a second signal are needed for the complete activation of the T cell. The CD28/B7 receptor/ligand system is one of the dominant costimulatory pat