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The activity of 7-methylbenz(a)anthracene metabolites in an in vitro-in vivo carcinogenicity test using mouse lung tissue

✍ Scribed by Flaks, Antonia; Sims, Peter


Book ID
123522565
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
257 KB
Volume
3
Category
Article
ISSN
0304-3835

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Evaluation of the carcinogenic activity
✍ A. Flaks; J. M. Hamilton; D. B. Clayson; P. Sims 📂 Article 📅 1972 🏛 John Wiley and Sons 🌐 French ⚖ 272 KB

## Abstract 7,12‐Dimethylbenz(a)anthracene and three of its metabolites were tested for carcinogenic activity by in vitro incubation with murine pulmonary tissue for 2 days followed by implantation of the explants into isologous mice. 7‐Hydroxymethyl‐12‐methylbenz(a) anthracene and 12‐hydroxymethyl