✦ LIBER ✦

The activation of procarcinogens to mutagens by cultured rat hepatocytes in the L5178Y/TK mutation assay

✍ Scribed by David E. Amacher; Simone C. Paillet

Book ID: 113250689
Publisher: Elsevier Science
Year: 1983
Tongue: English
Weight: 642 KB
Volume: 113
Category: Article
ISSN: 0165-1161
DOI: 10.1016/0165-1161(83)90242-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hamster hepatocyte-mediated activation o

Hamster hepatocyte-mediated activation of procarcinogens to mutagens in the L5178Y/TK mutation assay

✍ David E. Amacher; Simone C. Paillet 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 581 KB

THE L5178Y/TK GENE MUTATION ASSAY FOR TH

THE L5178Y/TK GENE MUTATION ASSAY FOR THE DETECTION OF CHEMICAL MUTAGENS

✍ David E. Amacher; Gail N. Turner 📂 Article 📅 1983 🏛 John Wiley and Sons 🌐 English ⚖ 609 KB

Ascorbate is not detectably mutagenic in

Ascorbate is not detectably mutagenic in the L5178Y TK+− cell mutation assay

✍ Amacher, David E.; Paillet, Simone C. 📂 Article 📅 1981 🏛 Elsevier Science 🌐 English ⚖ 555 KB

Metabolic activation of 3-methylcholanth

Metabolic activation of 3-methylcholanthrene and benzo(a)pyrene to mutagens in the L5178Y/TK assay by cultured embryonic rodent cells

✍ Amacher, David E. ;Paillet, Simone C. ;Zelljadt, Inna 📂 Article 📅 1982 🏛 Wiley (John Wiley & Sons) ⚖ 569 KB

Promutagen activation by rodent-liver po

Promutagen activation by rodent-liver postmitochondrial fractions in the L5178Y/TK cell mutation assay

✍ David E. Amacher; Gail N. Turner 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 922 KB

Development of an optimal S9 activation

Development of an optimal S9 activation mixture for the L5178Y TK+/− mouse lymphoma mutation assay

✍ Jenness B. Majeska; Dale W. Matheson; H. E. Holden 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 667 KB

In previously described activation systems [Clive D, Spector : Mutat Res 31:17-291 for the mouse lymphoma mutation assay the cofactor isocitrate is rapidly exhausted and the resultant loss of NADPH can halt metabolic processes. Presented here are data obtained with a nontoxic b'olance of NADP (1.4 m